Metabolic regulation of an obligate symbiosis in leaf beetles

Advisor: Hassan Salem

PhD Program: International Max Planck Research School (IMPRS) 'From Molecules to Organisms'
Location: Max Planck Institute for Biology

Project description
Recent findings from our group revealed that leaf beetles harbor an obligate bacterial symbiont throughout development. We also find that the specialized organs dedicated to housing and transmitting the symbiont exhibit unique metabolic and immunological profiles. The selected doctoral candidate will dissect the molecular factors ensuring the homeostasis of the symbiosis. Through a combination of comparative genomics and transcriptomics, with CRISPR/Cas transformations, the envisioned project is multidisciplinary in nature, and will further our understanding of a highly streamlined mutualism.

More information on Hassan Salem and a selection of recent publications can be found on his faculty page.

 

Requirements
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Application deadline: 6 February 2022

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