Directed evolution of Methanobrevibacter smithii in mice

Advisor: Ruth Ley & Jill Waters

PhD Program: International Max Planck Research School (IMPRS) 'From Molecules to Organisms'
Location: Max Planck Institute for Biology, Ley Lab

Project description

For this project, you will use germfree mice to develop a simplified bacterial model community that maximizes the fitness of Methanobrevibacter smithii in the mouse gut. Genetic underpinnings of adaptation of M. smithii to the murine gut environment will be explored.

More information on Ruth Ley and  Jill Waters and a selection of recent publications can be found on their pages.

 

Requirements
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Application deadline: 6 February 2022

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